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Epi-LASIK with intraoperative MMC for the correction of hyperopia and hyperopic astigmatism

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Session Details

Session Title: Presented Poster Session: Presbyopia

Session Date/Time: Saturday 05/09/2015 | 15:00-16:30

Paper Time: 16:00

Venue: Poster Village: Pod 2

First Author: : L.Speicher AUSTRIA

Co Author(s): :    W. Philipp              

Abstract Details


To evaluate visual and refractive outcomes after Epi-LASIK with prophylactic Mitomycin C (MMC) for the correction of hyperopia and hyperopic astigmatism.


Refractive Laser Center Innsbruck


In this retrospective study 28 hyperopic virgin eyes from 15 consecutive patients were included. Mean age of patients was 45.12 years (range 26-61). An epikeratome (Gebauer, Germany) was used to create the epithelial flap which was discarded after excimer laser ablation (Wavelight Allegretto Wave Eye-Q 400Hz, Germany). In astigmatic eyes, limbal marks denoted the horizontal axis. After photoablation, a sponge soaked in 0.02% MMC solution was applied for 20 seconds, followed by extensive irrigation with balanced salt solution. Visual acuity, possible corneal haze formation and refractive stability were evaluated early postoperatively and 6 to 12 months after surgery.


Preoperative hyperopia ranged from +1.25 to +4.0 D (mean +2,528 D) with up to - 4.0 D of astigmatism (mean -0.978 D). Early postoperative mean refractive error was -0.305 D (range -1.75 to +1.25 D) which stabilized at a mean value of +0,920 D late postoperatively. Mean cylindrical error was -0.529 D (range 0.00 to -1.25 D) early postoperatively and further improved to -0.402 D at 12 months. Early postoperative UCVA was 0.748 and improved to 0.924 at 12 months after surgery. Only trace haze was observed in 2 patients and there was no loss of BCVA in all patients.


Until now, only few data are available in the literature regarding the efficacy of MMC in hyperopic corrections. In the present study we could show that Epi-LASIK with intraoperative 0.02% MMC was efficacious to inhibit corneal haze formation and regression in patients with hyperopia up to +4.0 diopters. Interestingly, outstanding results could be obtained in patients with hyperopic astigmatism with stable results up to 1 year after surgery. MMC seems to be a useful adjunct for Epi-LASIK in hyperopia and hyperopic astigmatism.

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