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Natural history and incidence of rainbow glare and light scattering in femtosecond laser-assisted in situ keratomileusis

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Session Details

Session Title: LASIK II

Session Date/Time: Tuesday 08/09/2015 | 14:00-16:00

Paper Time: 15:33

Venue: Room 10

First Author: : R.Krueger USA

Co Author(s): :    K. Rocha   W. Dupps                 

Abstract Details


To assess the incidence and long-term outcomes of rainbow glare and light scattering in femtosecond laser-assisted in situ keratomileusis.


Prospective, randomized, contralateral eye study in a large group academic medical center, Cleveland Clinic Cole Eye Institute


50 myopic eyes underwent LASIK using the ALLEGRETTO®Eye-Q excimer laser with refraction ranging from -1.00 to -7.25 diopters (mean -3.31±1.9). Flap creation was randomized using the IntraLASE FS60 (IL) in one eye and WaveLight FS200 (FS) in the contralateral eye. Rainbow glare (subjective testing using bright focal light in scotopic environment) and light scattering test (C-Quant, Oculus Inc, Lynnwood, WA) were obtained preoperatively and at 1 week, 1, 3 and 9 months postoperatively. Manifest and wavefront refractions were performed at each postoperative visit.


Light scattering peaked at 1 week postoperatively in both IL and FS groups (log 1.28±0.16, p=0.02 and log 1.26±0.12, p=0.039, respectively) with statistically significant improvement at 3 months (log 1.11±0.35, p=0.007 and log 1.19±0.14, p=0.04) and 9 months (log 1.10±0.16, p=0.008 and log 1.14±0.13, p=0.011). 11 patients reported rainbow glare at 1 week, 9 at 1 month, 5 at 3 months and 6 at 9 months in the IL group and 14 patients at 1 week , 11 at 1 month, 5 at 3 months and 6 at 9 months in the FS group. No statistically significant differences were found between IL and FS groups.


The time course of rainbow glare and light scattering were quantified; both optical side effects were greatest at 1 week and significantly decreased between 1 month and 9 months postoperatively. Optical side-effects of femtosecond laser did not correlate with postoperative clinical outcomes. Rainbow glare and light scattering are mild optical side effects of femtosecond LASIK that gradually improve with time.

Financial Interest:

One of the authors receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented

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