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Patient-reported outcomes with wavefront-guided and wavefront optimized LASIK: a prospective study

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Session Details

Session Title: LASIK II

Session Date/Time: Tuesday 08/09/2015 | 14:00-16:00

Paper Time: 14:12

Venue: Room 10

First Author: : E.Manche USA

Co Author(s): :    J. Kung                    

Abstract Details


To compare the effect of wavefront guided (WFG) and wavefront optimized (WFO) LASIK on subjective quality of vision.


Academic Refractive Surgery Center Stanford University School of Medicine, USA.


The dominant eye in 55 participants with myopia were randomized to receive WFG LASIK treatment by the VISX CustomVue Star S4 excimer laser system (Abbott Medical Optics, Inc., Santa Clara, CA), while the fellow eye received WFO treatment by the Wavelight Allegretto Wave Eye-Q 400 Hz excimer laser system (Alcon Laboratories, Inc., Fort Worth, Texas). Subjects completed a questionnaire assessing quality of vision and visual symptoms (daytime and nighttime glare, daytime and nighttime clarity, halos, haze, fluctuating vision, double vision) preoperatively and at postoperative months 1, 3, 6, and 12.


The severity of symptoms increased at postoperative month 1 in both groups and trended toward baseline by one year. At 3, 6 and 12 months postoperatively, there was no significant difference in symptoms between WFG and WFO groups, although at 12 months WFG eyes were rated as having more excellent vision (P = 0.039). In the subgroup of patients with preoperative RMS HOA's less than 0.3 microns, WFO eyes reported worsened nighttime clarity (P = 0.009), daytime clarity (P = 0.015), and fluctuating vision (P = 0.046), as well as less excellent vision (P = 0.009) at 12 months.


One year after surgery, most patients' self-reported visual symptoms were similar in eyes receiving WFG or WFO LASIK. However, WFG eyes were rated as generally having more excellent vision, particularly in patients with lower baseline HOAs (RMS < 0.3 μm).

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