Barcelona 2015 Programme Registration Glaucoma Day 2015 Exhibition Virtual Exhibition Satellite Meetings Hotel Booking Star Alliance

Take a look inside the London 2014 Congress


Then register to join us
in Barcelona!

Hemi-Descemet's membrane endothelial keratoplasty: one year outcomes

Search Abstracts by author or title
(results will display both Free Papers & Poster)

Session Details

Session Title: Cornea: Surgical I

Session Date/Time: Tuesday 08/09/2015 | 08:00-10:30

Paper Time: 09:18

Venue: Room 10

First Author: : F.Lam UK

Co Author(s): :    L. Baydoun   M. Satue   M. Dirisamer   L. Ham   G. Melles        

Abstract Details


We evaluated the 1-year clinical outcomes after semi-circular Descemet membrane endothelial keratoplasty (hemi-DMEK) in this first case series in the world.


Netherlands Institute for Innovative Ocular Surgery. Tertiary referral center in Rotterdam, The Netherlands.


In three eyes of three patients with Fuchs endothelial dystrophy, best corrected visual acuity (BCVA), endothelial cell density (ECD), pachymetry, and intra- and postoperative complications were serially evaluated after transplantation of a semi-circular 12 mm diameter Descemet graft (hemi-DMEK graft).


All corneas cleared within 6 months and showed a stable pachymetry thereafter (527, 535 and 490 ┬Ám, respectively). Compared to preoperative measurements, average central ECDs dropped by 51% (56, 39, and 59% respectively) at three months, 53% (57, 38, and 63% respectively) at 6 months, and 59% (60, 47, and 71% respectively) at 12 months. Denuded stromal areas adjacent to the graft cleared and at 12 months peripheral ECD counts ranged from 724 to 1051 cells/mm2. At 12 months, BCVA was 20/22 (0.9), 20/40 (0.5, amblyopic eye) and 20/17 (1.2). No postoperative complications occurred throughout the study period.


Hemi-DMEK may provide visual outcomes similar to those in routine DMEK at one year post operation. If so, hemi-DMEK could become the next step in endothelial keratoplasty, owing to its potential to double the yield of transplants from the same donor pool (two hemi-DMEK grafts can be prepared from one donor cornea).

Financial Interest:

One of the authors receives consulting fees, retainer, or contract payments from a competing company

Back to previous