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DMEK in challenging cases

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Session Details

Session Title: Cornea: Surgical I

Session Date/Time: Tuesday 08/09/2015 | 08:00-10:30

Paper Time: 09:06

Venue: Room 10

First Author: : A.Saad FRANCE

Co Author(s): :    E. Guilbert   D. Gatinel                 

Abstract Details


To describe the results of DMEK surgeries in the presence of an anterior chamber IOL and post failed penetrating keratoplasty.


Rothschild Foundation, Paris, France


Prospective, observational case series of 30 eyes of 30 patients undergoing a DMEK surgery at the author's institution by a single surgeon. The endothelio-Descemet graft was manually prepared in the operating room and was inserted in the receiver Anterior Chamber using a dedicated single use injector after removal of the recipient Descemet membrane. All the surgeries were recorded. Clinical outcomes at 1,6 and 12 were obtained.


Twenty patients had DMEK surgery in the presence of an anterior chamber IOL (AC-IOL) and 10 patients had DMEK following a failed Penetrating Keratoplasty (PK). In both groups, 30% of the patients achieved a BCVA of 0.32 LogMar or better and all patients improved their VA by at least 2 lines. The average post-operative ECD was 1570 cells/mm2 in the post AC-IOL group and 1650 cells/mm2 in the post PK group. Mean unfolding time was 12 +/- 7 minutes in the post AC-IOL group and 8 +/- 5 mn in the post PK group. Most patients had comorbidities limiting improvement of the VA. Primary graft failure occurred in one patient in the presence of an AC-IOL.


DMEK might be a good option for patients suffering of corneal decompensation in the presence of an AC-IOL or post PK. In most cases, the AC-IOL might be maintained with good results.

Financial Interest:


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