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Small incision lenticule extraction (SMILE): results from treatment of more than 1000 eyes with myopic astigmatism

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Session Details

Session Title: Interactive Free Paper Session: Femtosecond Small Lenticule Extraction I

Session Date/Time: Monday 07/09/2015 | 09:00-11:00

Paper Time: 09:12

Venue: Room 19

First Author: : R.Hansen DENMARK

Co Author(s): :    N. Lyhne   J. Grauslund   A. Vestergaard              

Abstract Details


The aim of this study was to evaluate refractive predictability and visual acuity up to 3 months after SMILE treatment for all degrees of myopia.


Department of Ophthalmology, Odense University Hospital, Odense, Denmark.


Retrospective study of results after SMILE treatments. All treatments were performed from 2011 to 2014. Inclusion criteria:Corrected Distance Visual Acuity (CDVA) ≤ 0.10 (logMAR) before surgery, and no other ocular conditions than myopia up to -10 D with or without astigmatism of maximum 3 D. Exclusion criteria: Eyes having undergone re-treatment. All treatments were performed with a VisuMax® femtosecond laser (Carl Zeiss-Meditec, Jena, Germany). Lenticule diameter ranged from 6.00 to 6.60 mm. Maximum attempted spherical correction was -10.00 D. Clinical examinations were performed pre-operatively and at 1 day, 1 week and 3 months post-operatively.


Of 1150 treated, 983 eyes were included. Pre-operative spherical equivalent (SE) refraction averaged -6.77±1.74 D. Emmetropia was target refraction in 362 eyes. In these eyes, 83% had an UDVA ≤ 0.10 (logMAR) after 3 months. Of all eyes, 88% were within ±0.5 D of intended refraction, whilst 98% were within ±1.0 D at 3 months after surgery. The mean difference between attempted and achieved SE refraction was -0.08±0.71 D. Concerning astigmatism, 83% had ≤ 0.5 D after 3 months, compared to 53% before surgery (P=0.02). After 3 months, 13 eyes (1.3%) had lost 2 lines or more of CDVA.


SMILE seemed predictable and safe for treatment of all degrees of myopia and myopic astigmatism up to 3 months after surgery.

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