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Corneal collagen cross-linking for post-LASIK ectasia: three years follow-up

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Session Details

Session Title: Cross-Linking

Session Date/Time: Sunday 06/09/2015 | 08:00-09:30

Paper Time: 09:12

Venue: Main Auditorium

First Author: : D.Wajnsztajn ISRAEL

Co Author(s): :    B. Rosin   S. Frenkel   D. Landau   J. Frucht-Pery           

Abstract Details


To report the 3 year outcomes of corneal collagen crosslinking (CXL) treatment for progressive post-LASIK ectasia.


Hadassah Medical Center ,Hebrew University Hospital, Ophthalmology Department, Jerusalem, Israel


Retrospective review of files of patients who had CXL for post-LASIK ectasia between August 2007 and January 2015. Outcomes were best corrected visual acuity (BCVA in LogMAR), topographic maximum keratometry (Kmax) and cylinder during the first 3 years post-CXL. Procedures were done by Dresden protocol with regular or hypotonic riboflavin (UV-X ™ Specifications, IROC, Zurich, Switzerland). Statistical analysis was performed by Wilcoxon Rank Sum Test using Matlab 2013b, The Mathworks Inc, Natick MA.


Thirty four eyes of 27 patients had CXL for LASIK ectasia. Age±SD: 33±7.6yrs (22 to 57yrs). Kmax, topographic cylinder and BCVA changed 1 year post-CXL (n=33) from 53.3±6D to 51.5±5D (p=0.23), 3.1±2.8D to 2.5±1.4D (p=0.59) and 0.3±0.2 to 0.23±0.14 (p=0.14) respectively; 2yrs post-CXL (n=22) from 52.1±5.7D to 49.8±5D (p=0.20), 2.7±1.8D to 2.3±1.5D (p=0.50) and 0.26±0.21 to 0.19±0.12 (p=0.31) respectively; 3yrs post-CXL (n=13) from 54.4±5.7D to 50.7±5D (p=0.05), 3±2.1D to 1.9±1.1D (p=0.16) and 0.26±0.17 to 0.19±0.14 (p=0.20) respectively. One eye lost 2 lines of BCVA. There were 2 cases of sterile infiltrates, 1 deep lamellar keratopathy and 3 epithelial ingrowth (1mm).


CXL is a safe and efficacious procedure for treatment of progressing post-LASIK ectasia.

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