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Fungal endophthalmitis after Descemet stripping automated endothelilal keratoplasty due to endogenously infected grafts from the same donor

Poster Details

First Author: S.Palioura USA

Co Author(s):    K. Sivaraman   A. Sise   J. Batlle   D. Miller   G. Amescua   C. Karp

Abstract Details

Purpose:

To report two cases with post-operative Candida albicans endophthalmitis after Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) with grafts originating from the same donor.

Setting:

Tertiary ophthalmology referral center- Bascom Palmer Eye Institute, University of Miami

Methods:

Retrospective case series of two patients with late post-operative fungal endophthalmitis after DSAEK with corneal grafts from the same donor.

Results:

Two patients with Fuchs’ dystrophy underwent DSAEK by two corneal surgeons at different surgery centers. Both patients received a cornea from the same donor who had a history of presumed pulmonary candidiasis. Both patients were referred to Bascom Palmer Eye Institute with multifocal infiltrates at the graft-cornea interface one month later. Despite immediate explantation of the DSEK lenticules and intraocular antifungal injections both patients progressed to develop fungal endophthalmitis with the same strain of Candida albicans. Following penetrating keratoplasty with intraocular lens explantation, pars plana vitrectomy and serial intraocular antifungal injections, both are doing well at 6 months post-operatively.

Conclusions:

Fungal endophthalmitis due to infected donor corneal graft presents a management challenge and should prompt careful follow up of both recipients from the same donor. FINANCIAL DISCLOUSRE: NONE

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