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Longitudinal evaluation of DSAEK remodeling: graft, total corneal and corneal epithelium thickness evaluation by fourier domain anterior-segment OCT

Poster Details

First Author: C.Karabatsas GREECE

Co Author(s):    A. Kanellopoulos              

Abstract Details

Purpose:

To evaluate central graft thickness (CGT), corneal thickness (CCT) and corneal epithelial thickness (ET) changes following Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK).

Setting:

LaserVision.gr Clinical and Research Eye Institute, Athens, Greece

Methods:

Fourier-domain Anterior-Segment Optical Coherence Tomography (AS-OCT, Rt-Vue 100, OptoVue, Fremont, CA) was employed to obtain high-resolution meridional scans and corneal and epithelial thickness pachymetry maps pre-operatively and up to one-year postoperatively. 41 cases were investigated, 27 female and 14 male. Central corneal thickness and central graft thickness data were obtained using three caliper tool measurements, reporting the average of each per eye. Corneal pachymetry and epithelial pachymetry maps were employed to evaluate progressive rehabilitation over the course of one year.

Results:

Preoperative CCT was 589.78±49.24 (559 to 645) μm. One-month postoperatively, CCT was 736.26±34.52 (713 to 771) μm; CGT was 210.42±34.52 (145 to 243) μm. One-year postoperatively, CCT was 640.39±38.75 (569 to 684) μm; CGT was 153.15±42.91 (90 to 291) μm. Preoperative center epithelial thickness was 55.74±9.29 (45 to 74)μm, minimum 32.53±14.30 (13 to 53) μm, maximum 76.00±11.32 (64 to 105)μm, and topographic thickness variability 10.84±4.09 (5.90 to 18.80)μm. Three-months postoperatively, center epithelial was 47.21±5.45 (43 to 56)μm, minimum 35.11±4.70 (30 to 41)μm, maximum 58.11±6.51 (49 to 65)μm, and topographic variability 4.77±1.48 (2.90 to 6.50)μm.

Conclusions:

Anterior segment OCT is a valuable tool in following corneal transplant operations. Graft thickness, corneal and epithelial graft thickness appear to stabilize after one-month postoperatively following DSAEK. FINANCIAL DISCLOUSRE: One or more of the authors travel has been funded, fully or partially, by a company producing, developing or supplying the product or procedure presented

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