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Long-term visual function, efficacy, safety and endothelial cell loss after implantation of Artisan phakic intraocular lenses in patients with Myopia: 5 and 10 year results

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Session Details

Session Title: Refractive
Session Date/Time: Sunday 28/02/2016 | 08:30-11:00
Paper Time: 08:54
Venue: Skalkotas
First Author: : S.Jonker THE NETHERLANDS
Co Author(s): :    A. Ronden   T. Berendschot   I. Saelens   N. Bauer   R. Nuijts  

Abstract Details


Retrospective evaluation of visual and refractive parameters, efficacy, safety and endothelial cell loss in a large group of patients five and ten years after implantation with the Artisan phakic intraocular lens (pIOL) for myopia.


Academic Center for Refractive Surgery, University Eye Clinic Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands.


Data from all myopic patients implanted with the Artisan Myopia pIOL (Ophtec, Groningen, the Netherlands) from 1998 until November 2013 were collected for retrospective analysis. Eyes that underwent laser refractive touch-up were excluded from analysis (15 eyes). Mean preoperative age was 41.4±10.5 and 124 and 64 eyes respectively were evaluated after 5 and 10 years follow-up. Both visual and refractive, topographic and intraocular parameters and endothelial cell density were measured preoperatively, 1 day, 1 week, 1, 3, 6 and 12 months postoperatively, followed by annual visits after completing the first year follow-up.


Mean LogMAR UDVA was 0.26±0.29 and 0.36±0.34 LogMAR respectively 5 and 10 years postoperatively (p<0.01). Mean LogMAR CDVA was 0.05±0.15 and 0.10±0.29 LogMAR respectively 5 and 10 years postoperatively (p=0.02 and p<0.01 respectively). Mean spherical equivalent (SE) was -0.95±1.11 D and -1.57±1.57 D respectively 5 and 10 years postoperatively (p<0.01). After 5 and 10 years 64.8% and 46.6% of eyes were within 1.0 D of the intended correction. Mean chronic annual EC loss from 6 months to 5 and 10 years postoperatively was -1.00% and -1.39% respectively p.a. (p<0.01).


Over 10 years, uncorrected visual acuity showed a slight decline of 0.21 LogMAR due to a mean myopisation of -0.95 D. Best corrected visual acuity remained stable during 5 and 10 year follow up. There was a progressive annual endothelial cell loss of -1.39% p.a. that more than doubled the expected physiological endothelial cell loss of -0.6% p.a..

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