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First Author: C.Sales USA
Co Author(s): E. Manche
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To compare the quality of vision outcomes of wavefront (WF) guided and WF optimized LASIK.
Byers Eye Institute, Stanford University Department of Ophthalmology, Palo Alto, California, United States of America.
Seventy-two eyes of 36 subjects with myopia with or without astigmatism were randomized to receive either WF guided or WF optimized LASIK with the WaveLight® Allegretto Eye-Q 400 Hz excimer laser platform. WF guided treatments were planned using the Alcon Wavelight Allegro Analyzer (Alcon, Inc., Hüenberg, Switzerland). LASIK flaps were created using the 150-kHz IntraLase iFS (Abbott Medical Optics, Santa Ana, California). Patients were evaluated preoperatively and postoperatively at months 1, 3, 6, and 12. Evaluations included measurement of best spectacle corrected visual acuity (BSCVA) under controlled 5% and 25% contrast sensitivity conditions (Precision Vision, La Salle, Illinois). Patients also completed a questionnaire detailing subjective symptoms, which included quantitative grading on a scale of 0 (no symptoms) to 10 (severe symptoms) for each of the following parameters: glare under night and day conditions, haze, halos, clarity under night and day conditions, dry eye symptom frequency and severity, foreign body sensation, vision fluctuation, and ghosting. The LASIK surgeries were performed in a bilateral simultaneous fashion to negate any learning curve. Data are presented for month 12.
Preoperative data showed no statistically significant differences between the WF guided and WF optimized groups for the parameters of uncorrected visual acuity (UCVA), BSCVA, 5% and 25% contrast sensitivity, and all questionnaire variables (all P>0.05). At postoperative month 12, there were no statistically significant differences between the groups with respect to 5% and 25% contrast sensitivity (WFG vs. WFO: 0.23 ±0.16 vs. 0.26 ±0.16; 0.23 ±0.16 vs. 0.22 ±0.08 logMAR; P=0.78, P=0.74, respectively), and all of the subjective symptoms evaluated on the questionnaire (all P>0.05).
There were no differences at 12 months in quality of vision outcomes between WF guided and WF optimized LASIK using the WaveLight® Allegretto Eye-Q 400 Hz excimer laser platform in myopic patients with or without astigmatism.