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Epi-Bowman keratectomy vs alcohol-assisted PRK: healing process evaluation with spectral OCT with a novel speckle reduction technique

Poster Details

First Author: B.Kaluzny POLAND

Co Author(s):    I. Cieslinska   M. Szkulmowski   I. Grulkowski   M. Wojtkowski     

Abstract Details


Epi-Bowman Keratectomy (EBK) is a new variant of PRK in which epithelium is removed with the Epi-Clear device (Orca Surgical, Israel). The aim of the study is to compare epithelial healing process after EBK and conventional alcohol-assisted PRK subjectively and objectively with the use of Spectral OCT with a novel speckle reduction technique


Department of Ophthalmology, Collegium Medicum and Institute of Physics, Nicolaus Copernicus University, Torun, Poland, Oftalmika Eye Hospital, Bydgoszcz, Poland


A total number of 60 eyes with myopia or myopic compound astigmatism underwent laser refractive correction with the Amaris 750 S (Schwind eye-tech-solutions). In 30 cases EBK was performed (EBK group) and 30 eyes were treated with conventional PRK with epithelium removed with alcohol (PRK group). The outcome measures included: time of the epithelium removal, ease of epithelium removal, patient comfort during the surgery, pain in first hours and first days after the surgery and re-epithelialization time. SOCT measurements were performed before the surgery and once a day during the first postoperative week. The measurements were performed with SOCT device with central wavelength of the light source of 820nm and axial resolution of 4.2 ?m in tissue. A novel technique of reduction of the speckle contrast by averaging of 16 A-scans deflected orthogonally was implemented.


The following statistically significant differences were found: in EBK group mean time of the epithelium removal was 30 % shorter, epithelium removal was easier, patient comfort during the surgery was higher and re-epithelialization time was shorter. We did not observe significant differences in pain levels in first hours and first days after the surgery. Moreover, SOCT technique with novel speckle contrast reduction technique allowed to acquire tomograms of the cornea of outstanding quality and to detect some differences in epithelial healing process.


Epithelium removal technique used in EBK provides better comfort during the surgery for both the surgeon and the patient. Shorter re-epithelialization time may be linked with SOCT detectable differences in epithelial healing.

Financial Disclosure:

... research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented

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