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Evaluation of the impact of light scatter from glistenings in pseudophakic eyes

Poster Details

First Author: A.Doraiswamy USA

Co Author(s):    E. DeHoog              

Abstract Details



Purpose:

To study the impact of light scatter from glistenings in pseudophakic eyes using ray-tracing in a model eye

Setting:

Advanced Vision Science Inc

Methods:

A pseudophakic eye model was constructed in ZEMAX using the Arizona eye model as the basis. The lens was optimized for a polychromatic MTF for field angles 0, 1.4 and 2 Degrees corresponding with Foveal vision. Mie scattering theory is used to describe the intensity and direction of light as it scatters for a spherical particle immersed in a given media (IOL). The modeling and evaluation of scatter and modulation transfer function (MTF) are performed for various biomaterials for various size and density of glistenings under scotopic, mesopic, and photopic conditions.

Results:

As predicted by Mie theory, the amount of scatter is a function the relative difference in refractive index between the media and the scatterer, the size of the scatterer and volume fraction of the scatterers. From this simulation we have demonstrated that an increase in density of glistenings can lead to significant drop in MTF. This effect is more pronounced in lenses with smaller cavitations. In general, higher index materials will result in higher scattering due to the larger change in index. However, lens thickness has a large influence on scattering due to the increased propagation distance increasing the probability of scatter.

Conclusions:

Mathematical modeling of glistenings in pseudophakic eyes demonstrated that higher density of glistenings in various sizes and in various materials can lead to a significant loss in MTF of the IOL and thus a noticeable reduction in image contrast and quality of vision.

Financial Disclosure:

... is employed by a for-profit company with an interest in the subject of the presentation

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