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Treatment of recurrent corneal epithelial defect using autologous serum eye drop: a case series

Poster Details

First Author: H.Norouzi IRAN

Co Author(s):    H. Mohammad Rabei   K. Sheibani           

Abstract Details


To evaluate the efficacy of autologous serum application for the treatment of recurrent corneal epithelial defect.


Imam Hossein Medical Center. Tehran, Iran.


A total of 14 patients with recurrent corneal epithelial defect were studied. Autologous serum was prepared from the patients and diluted to 20% adding normal saline. The patients were instructed to use the autologous serum every six hours. Patients were followed for a mean period of 18 months.


Four male (%28.6) and 10 (% 71.4) female patients entered the study. Four patients stopped the treatment after three months with complete satisfaction from treatment. Patients reported a reduction in frequency and severity of attacks 2ḟ4.6weeks after the start of treatment. The mean number of attacks before the procedure was 0.9ḟ7.6 per year which was reduced to 0.9ḟ2.2 per year after treatment (p<0.001). The main side effects in patients were eye peruritus and redness which were well tolerated by patients.


Autologous serum application seems to be a safe and effective method to treat recurrent corneal epithelial defect.

Financial Disclosure:


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