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Toxic optic neuropathy

Poster Details

First Author: R.Sharma UK

Co Author(s):    V. Bansal              

Abstract Details



Purpose:

Case Report of Toxic Optic Neuropathy (TON) secondary to Anti-Tuberculosis treatment

Setting:

46 years male, referred with suspicious looking optic discs, seen at Department of Ophthalmology, Colchester, UK. Past medical history significant, with patient under the care of multi-disciplinary team for treatment of tuberculous arthritis and osteomyelitis. Medications included oral anti-tuberculosis treatment. Past ocular history revealed being seen as papilloedema. No allergies to medications recorded.

Methods:

Visual acuity, pupillary reactions, anterior segment examination and intraocular pressure were unremarkable. Color vision slightly reduced in left eye. Humphrey visual field tests revealed inferonasal visual field defects.

Results:

Bilateral disc swelling, which reduced significantly after the change in the oral anti-tuberculosis treatment.

Conclusions:

Anti-Tuberculosis treatment drugs especially Ethambutol and Isoniazid, have been implicated in Toxic Optic Neuropathy (TON). Diagnostic features, investigations and Isoniazid induced TON management plan will be presented.

Financial Disclosure:

NONE

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