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Correlation of refractive error and pulsatile ocular blood flow in healthy eyes

Poster Details

First Author: J.Koh SOUTH KOREA

Co Author(s):    C. Choi              

Abstract Details



Purpose:

The purpose of this study is to evaluate the correlation of refractive error and pulsatile ocular blood flow (POBF) analysis in healthy eyes.

Setting:

Department of Ophthalmology, Chosun University College of Medicine,Gwangju, Republic of Korea

Methods:

A total of 104 subjects (52 men and 52 women) were included in this study. One eye of each participant was randomly selected and assigned to one of four refractive groups: hyperopes (N=20, mean spherical equivalent (MSE)?+1.00D), emmetropes (N=28, MSEḟ0.75D), lower myopes (N=33, MSE -1.00 to -4.75D), and high myopes (N=23, MSE?-5.00D). The pulsatile ocular blood flow (POBF), pulse amplitude, pulse volume, and pulse rate were analyzed using an ocular blood flow analyzer (OBF). Intraocular pressure (IOP) and axial length were measured.

Results:

The pulsatile component of ocular blood flow (POBF, pulse amplitude, and pulse volume) showed positive correlation with MSE and showed negative correlation with axial length (r=0.781, p<0.001 and r=-0.771, p<0.001, respectively). In high myopes, pulsatile component of ocular blood flow was lower than in lower myopes, emmetropes, and hyperopes. No significant difference in age or IOP was observed among the four groups. No significant correlation was found between POBF and age or IOP.

Conclusions:

In this study, the POBF increased as MSE increased and decreased as axial length increased. In addition, we observed that POBF was unaffected in eyes with healthy low myopes, emmetropes, and hyperopes, but decreased in eyes with healthy high myopes.

Financial Disclosure:

NONE

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