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Visual results of topography-guided laser in situ keratomileusis: femtosecond laser versus mechanical microkeratome

Poster Details

First Author: A.Jain INDIA

Co Author(s):    S. Karkhur   J. Ram   P. Kumar   C. Malhotra   R. Gupta   P. Chakma

Abstract Details


To compare and evaluate the predictability, stability, safety, efficacy and change in ocular aberrations after topo-guided LASIK with ?ap created by femtosecond laser (iFS 150 Hz) and mechanical microkeratome – One Use Plus SBK (Moria SA).


Advanced Eye Center, PGIMER – Chandigarh, India


Prospective , nonrandomized, comparative clinical study 80 eyes (40 patients) with myopia and myopic astigmatism were distributed into 2 groups i.e. 40 [20 patients] eyes for each group. Patients in group A had LASIK flap creation with iFS (Intralase femtosecond laser 150Hz) and in group B with One Use-Plus SBK (Moria SA). All eyes underwent topo-guided (ATLASTM 9000, Zeiss) LASIK on MEL 80 [Zeiss] excimer Laser. Preoperative, one month and 3 month postoperative wavefront errors from the cornea (ATLASTM 9000,Carl Zeiss, Germany) were calculated over 4mm and 6mm diameter and decomposed into Zernike polynomials to the 6th order.


Both groups were matched in terms of age, sex, spherical equivalent, pachymetry and keratometry total higher order, spherical and coma aberrations. Both procedures were safe, efficacious, stable and predictable to the same extent. Visual recovery was quicker in femtosecond group. In first post operative week 88% eyes in femtosecond group achieved postoperative UCVA of 20/20 or better which was significantly higher [<0.001] than in the mechanical micro- keratome group[54%] . At the end of 3 months 48% achieved the UCVA of 20/16 in femtosecond laser group against 33% in microkeratome group. Post operative total corneal high-order aberrations, spherical and coma aberrations decreased significantly from pre-operative values [p< 0.00] in both groups at 6mm only, but there was no significant difference between two groups at the end of one month and 3 months post-operatively.


Visual outcomes of topography guided LASIK procedure with MEL 80 , in which ?aps were created with either femtosecond laser (iFS 150Hz, AMO) or mechanical microkeratome (Moria Evo3 One Use-Plus, Moria SA) were same in terms of safety, efficacy, predictability, stability and decrease of higher order aberrations at the end of 3 month follow up.

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