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First Author: K.Kawai JAPAN
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We previously reported that long-term immersion of acrylic intraocular lenses (IOLs) in water at high temperature leads to their opacification and deterioration. This study aimed to examine changes in the cut surface and weight of colored acrylic IOLs (colored IOLs) after 115 days of the severe accelerated deterioration test.
Department of Ophthalmology Tokai University School of Medicine
Colored IOLs manufactured by various companies were immersed in 50-mL screw-tube bottles containing ultrapure water at 100?C for 115 days (equivalent to 20 years). External appearance and cut surfaces were observed before and after drying of the IOLs, and then percent changes in weight before and after treatment were determined. IOLs used: We used 3 colored IOLs of each of the following 5 types manufactured by different companies?SN60WF (Alcon) and AN6K (KOWA) by the cast-molding method and NY-60 (HOYA), NX-60 (Santen), and NS-60YG (NIDEK) by the lathe-cut method.
External appearance: Opacification was observed to a varying degree in all IOLs except AN6K and NX-60. After drying at a room temperature of 25?C for 48 hours, opacification disappeared in all IOLs except SN60WF. Cut surfaces: Opacification was observed to a varying degree for all IOLs. After drying, opacification was observed in all except NS-60YG. Percent changes in weight: Percent changes in weight before drying were unmeasurable for SN60WF, -3% for AN6K, -0.9% for NY-60, +2.3% for NX-60, and +0.6% for NS-60YG. The changes after drying were -1.5% for SN60WF, -9.8% for AN6K, -2.7% for NY-60, -3.7% for NX-60, and -1.5% for NS-60YG.
There were differences in opacification among cut surfaces of IOLs. Percent changes in weight before and after drying differed by approximately 6% for AN6K and NX-60. These differences may be attributable to different methods of manufacturing acrylic resin.
... receives non-monetary benefits from a company producing, developing or supplying the product or procedure presented.