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First Author: L.Lim SINGAPORE
Co Author(s): R. Wei S. Zhao D. Tan
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To evaluate the characteristics of unilateral keratoconus (KC) defined on the basis of corneal topography and to analyse videokeratography parameters between fellow eye and normal controls.
Singapore National Eye Centre
A total of 111 patients with clinical KC were prospectively enrolled. Corneal topographies of both eyes were evaluated with Tomey and Orbscan II corneal topography system. The patient was labelled as unilateral KC if one eye had clinical KC, and the other eye did not have any topographic signs of KC such as asymmetric videokeratographic pattern; positive result in Tomey KC screening system; maximum posterior elevation more than 40?m; or corneal thinnest pachymetry less than 500?m. Clinical characteristics and 13 Orbscan II quantitative indices between two eyes and normal control group were evaluated.
Five (4.5%) of the 111 patients with KC had no topographic evidence of KC in the fellow eye. All clinically normal fellow eyes had symmetric bowtie patterns. There were statistically significant differences in maximum posterior elevation, corneal irregularity, and corneal thinnest values between KC eyes and fellow eyes, and between KC eyes and control eyes. Only 3mm irregularity was significantly higher in the fellow eyes compared with control group (p<0.05). An increased trend for corneal 5mm irregularity was found in fellow eyes compared to controls.
The incidence of unilateral KC was 4.5%. We found a trend of higher irregularity in fellow eyes compared with controls. This finding indicates that the fellow eyes may show a certain low-expressivity morphologic feature of KC.