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First Author: E.Cetin TURKEY
Co Author(s): S. Acer M. H?raali S. Fenkci G. Pekel R. Ya?c? A. Avunduk
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To assess anterior segment findings by Pentacam HR® in patients with Graves Disease (GD).
Pamukkale University, Department of Ophthalmology, Denizli, Turkey
Patients with GD were included in this prospective study. Central corneal thickness (CCT), corneal volume, anterior chamber volume (ACV), anterior chamber depth (ACD), and keratometry were assessed by Pentacam HR® in all participants. The patients with diseases that may affect cornea or prevent optimal imaging were excluded.
A total of 11 patients with GD (9 eyes with thyroid eye disease (TED) and 13 eyes without TED) and 11 healthy controls were included in the study. The mean age of the patients was 39.6ḟ12.4 in the study group and 40.2ḟ6.8 in the control group (p=1.0). Seven patients were female and 4 were male in the study group and 8 were female and 3 were male in the control group (p=1.0). The mean keratometry (K1 and K2), CCT, corneal volume, ACV and ACD were 42.8ḟ1.5,43.1ḟ0.2,545.7ḟ34.4, 60.3ḟ2.5, 171.5ḟ32.4 and 2.9ḟ0.3 in the study group and 44.3ḟ1.2, 45.5ḟ1.3, 551.5ḟ48.9, 62.0ḟ5.5, 146.8ḟ33.7 and 2.8ḟ0.2 in the control group respectively (p=0.002, p<0.001, p=0.842, p=0.336, p=0.022 and p=0.549 respectively). When the eyes with TED were compared with the eyes without TED in the study group, only the difference in ACD was significant with lower values in eyes with TED (p=0.045).
Flatter average keratometric readings and smaller ACV were obtained in eyes of patients with GD compared to eyes of healthy controls. ACD was shallower in eyes with TED compared to eyes without TED in patients with GD.