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Can we retrieve individual endothelial cells in the postoperative course after implantation of a phakic posterior chamber lens?

Poster Details

First Author: D.Böhringer GERMANY

Co Author(s):    M. Daniel   L. Bredow   T. Reinhard        

Abstract Details



Purpose:

To rule out subtle chronic corneal endothelial cell (CEC) loss after cosmetic myopia correction by means of a phakic intraocular lens. Small degrees of CEC loss cannot be ruled out on the basis of two CEC density measurements as a matter of principle. This could be rather achieved by means of retrieving exactly the same CEC mosaic in later specular micrographs.

Setting:

We retrospectively analyzed the postoperative specular micrographs (Robo-Nocon) of 28 eyes after implantation of a phakic posterior chamber lens.

Methods:

We dotted all CEC centroids and tried to match the dot pattern with later images of the same eye. Whenever this was possible, we aligned the images accordingly and performed a flicker comparison.

Results:

We retrieved corresponding areas in central CEC mosaic in 25 of all 28 eyes (90%). The first postoperative specular micrgraph had been mostly taken after 6 months postoperatively (median). The second specular micrograph was mostly recorded 19 months later (median). In all but one pair, we ruled out CEC loss completely in the overlapping area. In one pair, the quality was insufficient to rule out CEC loss completely.

Conclusions:

We herein report for the first time that it is possible to retrospectively retrieve the CEC mosaic many months after intraocular surgery on the basis of routine non-contact specular micrographs. Therefore, we can rule out any systematic low-grade chronic CEC loss in the central cornea during 19 months following implantation of a phakic posterior chamber lens.

Financial Disclosure:

NONE

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