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First Author: H.Bayhan TURKEY
Co Author(s): S. Aslan Bayhan ?. Can
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To compare the corneal volume in keratoconus patients and healthy controls and to evaluate the association between corneal volume and corneal curvature
Bozok University Faculty of Medicine, Yozgat, Turkey.
57 eyes of 42 keratoconus patients and 30 eyes of 30 controls were included in this prospective study. Corneal volume measurement for 10 mm diameter was obtained for each eye with the Sirius Scheimpflug-Placido topographer (CSO, Italy). Corneal volume of keratoconic and control eyes were compared. The relationship of corneal volume with corneal curvature and minimum corneal thickness was assessed using Pearson correlation analysis.
Corneal volume, the flattest and steepest keratometry and minimum corneal thickness values in the keratoconus group and control group were 53.39ḟ3.72 mm3 and 56.30ḟ2.9 mm3, 46.54ḟ3.50 D and 42.73ḟ1.21 D, 51.49ḟ4.84 D and 43.58ḟ1.25 D, 442.56ḟ41.25 ṁm and 524.46ḟ33.07 ṁm, respectively. Corneal volume was significantly less in the keratoconus group than that of the control group (p<0.001). Corneal volume was negatively correlated with corneal curvature (r=-0.355 p=0.003) and positively correlated with minimum corneal thickness (r=0.662 p<0.001).
Corneal volume was decreased in keratoconic eyes indicating corneal tissue loss in keratoconus and these finding could help clinicians to better discriminate between normal and ectatic cornea.