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First Author: J.Seo SOUTH KOREA
Co Author(s): T. Kim
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To investigate the characteristics of the lamina criborsa (LC) depth in healthy eyes using enhanced depth imaging optical coherence tomography (EDI OCT).
Cross- sectional study/ Seoul National University Bundang Hospital
Three hundred eyes of 150 healthy subjects enrolled. Serial horizontal B-scans of optic nerve head were scanned using EDI OCT for both eyes of each normal subject. The LC depths were measured on B scan images obtained at 7 planes, which divided into vertically equal octuplicate LC. The comparisons of the LC depths in inter-eye were performed. In addition, the association of gender, age, refractive errors, intraocular pressure, central corneal thickness, and axial length with LC depth was assessed using linear mixed model. LC depths variation and symmetry in healthy subjects, and the factor correlated with LC depths.
The average LC depth was 402.06 ±101.46 ṁm (range: 193.08 - 826.81). The LC depths were strongly correlated (Pearsons correlation coefficients = 0.808 - 0.890, P <0.0001), were not significantly different between right and left eyes (All Ps > 0.05). Male had significantly greater LC depth than that of female (P < 0.0001). Comparison of the LC depth according to plane showed central ridge.
This study provided a range of normal LC depth for Korean subjects. In addition, the LC depth showed strong correlation between right and left eye. Given the significant differences between male and female, normative database of LC depth study should consider gender.