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First Author: B.Satana TURKEY
Co Author(s): C. Altan B. Basarir T. Sat?c? Y. Kucuksumer E. Bozkurt A. Demirok
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Purpose: To evaluate Pascal dynamic contour tonometry ( DCT) and ocular pulse amplitude (OPA) measurements in patients with asymmetric cupping of the optic nerve.
Settings: Cross sectional study was included the 86 eyes of 43 patients. Early POAG (11) and normal (32) patients who had eye examination between Febuary 2012 and June 2012 included to the study.
The inclusion criteria was having asymmetric cup to disc (C/D) ratio between two eyes equal or more than 0.2 The main outcomes of the study which were best corrected visual acuity (BCVA), intraocular pressure (IOP) with Goldman applanation tonometry (GAT) and DCT, Central corneal thickness (CCT), Axial length (AL), peripapiller retinal nerve fiber layer (RNFL) analysis via Ocular coherence tomography and OPA with DCT were compared between two eyes.
Results: The mean age of 25 male and 18 female study group was 50,3ḟ14,2 years. The mean C/D ratio of bigger optic disc cupping was 0,6ḟ0,1 while in smaller cupping eyes was 0,3ḟ0,1 (p<0,001). There was not statistically significant difference in BCVA, IOP-GAT, CCT, AL and RSLT between normals and early POAG group (p>0,05). The mean IOP-DCT and OPA of eyes with higher C/D ratios were in all patients 20,7ḟ3,7 and 3,5ḟ1,4; in normal group 20,1ḟ3,4 and 3,4ḟ1,5 and in early POAG group 22,6ḟ3,9 and 3,9ḟ1,2 while these values in eyes with lower C/D ratios were respectively 20,3ḟ3,5 and 3,3ḟ1,3; 20,0ḟ3,6 and 3,1ḟ1,3; 21,0ḟ3,5 and 3,8ḟ1,2 mmHg (p> 0.05).
Conclusion: There was no difference in OPA which is measuerd by DCT between the eyes of same patient who have asymmetry in C/D ratios. In glaucoma pathophysiology, to better understand the role of OPA which is an indirect measure of pulsatile ocular blood flow, further large scale studies were needed.