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Results of selective laser trabeculoplasty (SLT) for open angle glaucoma (OAG) over a 10 year period

Poster Details

First Author: A.Porta ITALY

Co Author(s):    F. Ferentini              

Abstract Details



Purpose:

To investigate the tonometric results and the survival of a group of 130 eyes with open-angle glaucoma (OAG) treated with Selective Laser Trabeculoplasty (SLT) in March 2003. Our target was to achieve and maintain an IOP reduction of 20% or more from the base line values at the different follow-up times

Setting:

Eye Unit, C. Cantù Hospital, Abbiatergrasso, Milan, Italy

Methods:

The results were collected at 1 week, 3 and 6 months and then every 6 months until today. The 180Ḟ inferior trabecular meshwork were treated with SLT. The population of 130 eyes is divided in this way: 12 eyes had a new diagnosis of glaucoma and were treated with the laser without any prior medical treatment; 118 eyes, already on treatment with eye drops, were divided into 2 sub-groups: 65 manteined the previous therapy in order to see the IOP variation obtained from SLT as an additive treatment, 53 eyes reduced the previous medical therapy to assess the possibility of replacing their drops after SLT procedure, improving the quality of life of patients

Results:

After 10 years, 50 eyes out of 130 survived; 46 eyes were excluded for post-SLT surgery, 15 excluded for changing therapy for visual field deterioration but valid IOP or loss of effectiveness of previous treatments, 17 lost during follow-up, 2 excluded for severe Basedow desease. Their pre-operative IOP was 19.2(SD:3.2) mmHg (range 22-32). From the baseline IOP value, the IOP reduction obtained is -25.37% (p< 0.001), average 14.33 mmHg. Regarding the single groups: the IOP average was 13.88(SD:2.64) mmHG for the eyes maintaining the same therapy, 13 eyes maintained the success criteria at any single follow up time visit, 14 eyes were considered “non responders” not achieving an IOP reduction of 20% or more at least in 3 months time, 8 eyes were considered “slow responders” obtaining the success criteria only in 3 months time but not before. The IOP average was 14.39(SD:1.75) for those changing their medical treatments, 4 eyes maintained the success criteria at any single follow up time visit, 13 eyes were considered “non responders”, 6 eyes were considered “slow responders” . The 12 eyes with recent diagnosis started from an IOP average of 24.16(SD:3.9) mmHg, dropping to 16.07(SD:1.59) mmHG, 5 excluded for post laser cataract procedure

Conclusions:

SLT is a minimally invasive technique that has proven to be safe, more it showed an excellent effectiveness even after a long follow-up time. Therefore SLT can be considered an excellent additional treatment or a valid alternative to traditional medical therapies. In the group with newly diagnosed glaucoma SLT is more effective than in eyes under previous medical therapies

Financial Disclosure:

NONE

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