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Effect of myopia on measuring peripapillary retinal nerve fiber layer thickness

Poster Details

First Author: H.Helaly EGYPT

Co Author(s):                  

Abstract Details


To assess the influence of axial length and refractive status of the eye on retinal nerve fiber layer (RNFL) thickness in myopic eyes measured by spectral domain optical coherence tomography (OCT).


Faculty of Medicine, Alexandria University, Egypt.


This study included 60 eyes of 60 myopic healthy individuals. Patients with a history of glaucoma or any other concurrent ocular disease were excluded. The peripapillary RNFL thickness was measured using a spectral domain optical coherence tomography. An average of 3 good quality scans was used to get the thickness of the RNFL.


The uncorrected inferior RNFL thickness showed the highest correlation with AL (r = - 0.81, r2 = 0.66, p <0.0001) followed by the superior and temporal. The uncorrected nasal RNFL thickness showed the weakest correlation (r = - 0.27, r2 = 0.07, p = 0.038). After correction of the RNFL thickness using the Littmann formula (t = p X q X s), the superior and inferior quadrants showed weaker correlation with the AL than the uncorrected values


Both axial length and spherical equivalent affect the RNFL thickness measurements. To ensure better accuracy, clinicians should consider correcting for the axial length-induced ocular magnification. Superior, Inferior and nasal RNFL thickness were thinner in myopic eyes. While temporal RNFL thickness was thicker in myopic eyes.

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