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First Author: A.Deka INDIA
Co Author(s): S. Saikia
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To evaluate the efficacy of prophylactic intracameral antibiotics in preventing endophthalmitis in cataract surgery.
This noncontrolled prospective interventional study included all cases of Phacoemulsification surgery from January 2009 to December 2011. Topical antibiotic was prescribed three days prior to surgery. The patients were classified into 3 groups. The first control group (no 548) had surgery without intracameral antibiotic. Second group (no 287) had surgery with intracemeral moxifloxacin (0.1 ml of 0.5% ophthalmic solution) and third group (no 201) had surgery with intracemeral cefuroxime (1mg/0.1ml), instilled at the end of surgery. All cases of postoperative endophthalmitis were related.
The rate of postoperative endophthalmitis was lower in the cases with intracameral injection at the end of surgery (group B 0.1.6% & group C 0%) than in those without intracameral injection (2.5%). No patients in the groups with intracameral injection developed TAAS, corneal endothelium or retinal toxicity.
Intracameral injection in cataract surgery, probably reduces the rate of postoperative endophthalmitis without toxic effects on the cornea or retina. However, it is not absolute and other factors need to consider avoiding endophthalmitis.