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Effects of corneal collagen cross-linking on ocular aberrations and contrast sensitivity in patients with keratoconus

Poster Details

First Author: S.Zarei-Ghanavati IRAN

Co Author(s):    A. Vojdani   H. Khakshoor           

Abstract Details



Purpose:

To compare ocular aberrations and contrast sensitivity before and after corneal collagen crosslinking

Setting:

Khatam-al-Anbia Eye Hospital, Mashhad, Iran

Methods:

22 eyes with keratoconus underwent CXL. Uncorrecteddistance visual acuity (UDVA),best spectacle–corrected visual acuity (BSCVA), contrast visual sensitivity test and higher-order aberrations before and 1, 3, 6 and 8 months after CXL, were measured.

Results:

The mean total HOA in 22 eyes of eleven patients with keratoconus underwent CXL, were measured 2.24, 2.34, 2.28, 2.17 and 2.03 micrometer in before and 1, 3, 6 and 8 months after CXL, respectively (p<0.01; except for 3rd month). Decreasing in other HOAs including vertical coma, horizontal coma, vertical trefoil, horizontal trefoil and Spherical Aberration observed in 6 and 8 months after CXL which except horizontal coma, all were significant (p<0.01). UCVA and BSCVA increased significantly in all months after CXL in proportion of before CXL (p<0.001). Although mean CVS declined significantly, improved significantly in 3rd, 6th and 8th months (p<0.00001).

Conclusions:

Corneal collagen crosslinking decreases high-order aberrations and improves contrast sensitivity in patients with keratoconus.

Financial Disclosure:

NONE

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