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Effects of corneal collagen cross-linking on ocular aberrations and contrast sensitivity in patients with keratoconus

Poster Details

First Author: S.Zarei-Ghanavati IRAN

Co Author(s):    A. Vojdani   H. Khakshoor           

Abstract Details


To compare ocular aberrations and contrast sensitivity before and after corneal collagen crosslinking


Khatam-al-Anbia Eye Hospital, Mashhad, Iran


22 eyes with keratoconus underwent CXL. Uncorrecteddistance visual acuity (UDVA),best spectacle–corrected visual acuity (BSCVA), contrast visual sensitivity test and higher-order aberrations before and 1, 3, 6 and 8 months after CXL, were measured.


The mean total HOA in 22 eyes of eleven patients with keratoconus underwent CXL, were measured 2.24, 2.34, 2.28, 2.17 and 2.03 micrometer in before and 1, 3, 6 and 8 months after CXL, respectively (p<0.01; except for 3rd month). Decreasing in other HOAs including vertical coma, horizontal coma, vertical trefoil, horizontal trefoil and Spherical Aberration observed in 6 and 8 months after CXL which except horizontal coma, all were significant (p<0.01). UCVA and BSCVA increased significantly in all months after CXL in proportion of before CXL (p<0.001). Although mean CVS declined significantly, improved significantly in 3rd, 6th and 8th months (p<0.00001).


Corneal collagen crosslinking decreases high-order aberrations and improves contrast sensitivity in patients with keratoconus.

Financial Disclosure:


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