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Massive corneal remodelling following corneal collagen cross-linking (CXL)

Poster Details

First Author: Z.Varga SWITZERLAND

Co Author(s):    F. Hoogewoud   T. Seiler   F. Hafezi        

Abstract Details



Purpose:

To evaluate the long-term refractive and topographic parameters of patients with the rare (1:200 CXL) and massive remodeling of the anterior corneal surface after corneal collagen cross-linking in an interventional case series.

Setting:

All patinets were treated and followed up at the Institute of Refractive and Ocular Surgery, Zurich, Switzerland or at the University Hospitals of Geneva, Geneva, Switzerland.

Methods:

Patients with progressive keratoconus had epi-off CXL performed following the standard protocol. Only patients with a massive remodeling of more than 6 diopter flattening within the first 12 postoperative months were included. Preoperative and postoperative BCVA, manifest refraction and Scheimpflug imaging of the cornea were recorded.

Results:

Significant changes were seen in BCVA, refractive cylinder, and anterior Kmax (average of 7.25D). Changes have been stable for over 24 months (range 6-38 months) On Scheimpflug imaging the posterior corneal elevation increased by 20 microns, the mean posterior K increased by 0.15D and the thinnest corneal thickness was reduced by 92 microns.

Conclusions:

In cases with massive corneal remodeling following CXL, anterior corneal surface topography appears to be stable up to 3 years. Most interestingly, the anterior topographic changes do not appear to be mirrored by similar changes in the posterior corneal surface.

Financial Disclosure:

NONE

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