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Corneal collagen cross-linking in the treatment of progressive keratoconus: analysis of remote results

Poster Details

First Author: E.Solodkova RUSSIA

Co Author(s):                  

Abstract Details



Purpose:

to determine changes in clinical, morphological and topographical values of the cornea, measured by means of Scheimpflug-analyser and anterior segment optical coherence tomography in remote post-surgical period. Changes induced by a conventional versus modified crosslinking with a depth-metered excimer laser deepithelialization were compared.

Setting:

The S.N. Fyodorov Eye Microsurgery Federal State Institution, Volgograd Branch

Methods:

a retrospective follow-up of 25 patients with I-III degree keratoconus was performed. Two patient’ cohorts were studied: 9 patients (9 eyes) after conventional CXL and 16 patients (16 eyes) after modified CXL with a depth-metered deepithelialization by excimer laser Schwind Amaris (Schwind Inc., Germany). Exposition to ultraviolet A was made by means of ḋUV-XṠ device (IROC Inc., Switzerland). Best-corrected visual acuity (BCVA), non-corrected visual acuity (NCVA), spherical equivalent (SEQ), minimal corneal curvature radius (Rmin), surface regularity index (SRI), surface asymmetry index (SAI) were measured preoperatively and 1, 3, 6, 12 months post-op.

Results:

1 year post-op NCVA and BCVA was higher in the 1 group (? < 0,01). SEQ dropped by 2,0 ḟ0,25 D in the I group and by 3,0 ±0,25 D in the II group (? < 0,05). Reduce in corneal thickness due to its compaction at the top of keratoconus was registered in the early follow-up period (by 10ḟ2 ṁm in the I group and by 5ḟ1 ṁm in the II group), (?> 0,05). Improvement in pachymetric values and in SRI/SAI findings was achieved by 6-months follow-up.

Conclusions:

one year postoperatively a considerable amelioration of both objective and subjective findings was noted in the studied groups, with a similar clinical efficiency of both CXL methods.

Financial Disclosure:

NONE

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