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First Author: G.Asimellis GREECE
Co Author(s): A. Kanellopoulos
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To evaluate safety, efficacy and ease of measurement of epithelial thickness changes after partial topography-guided ablation and high-fluence cross-linking with riboflavin.
Laservision.gr eye Institute, Athens, Greece
Twenty keratoconic eyes were subjected to partial topography-guided ablation and high-fluence cross-linking with riboflavin. We investigated postoperative epithelial healing (thickness and topographic thickness distribution) with anterior-segment optical coherence tomography (AS-OCT), in comparison to a control non treated, age-matched keratoconic population
The epithelium thickness showed an overall three month post-operative reduction. Specifically, mean thickness was preoperatively 55.65 ±1.22 ?m, and postoperatively, 40.60 ±1.22 ?m. Topographic epithelial thickness variability was also reduced, from 9.80 ±0.41 ?m, preoperatively to 5.37 ±0.40 ?m postoperatively. Statistically significant differences were observed when compared to the control group.
AS OCT imaging also supports a thinner and more homogeneous epithelium in cross-linked eyes, as introduced by a previous study of ours based on a different imaging modality. The ease of use and the increased predictability offered by AS-OCT, may be a significant advantage.
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