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Long-term results of collagen cross-linking using riboflavin and ultraviolet: a light for progressive keratoconus

Poster Details

First Author: M.Alfayez SAUDI ARABIA

Co Author(s):                  

Abstract Details


To prospectively evaluate the long-term safety and efficacy of collagen crosslinking for management of progressive keratoconus.


Institutional: The Eye and Laser Centre & King Abdulaziz University Hospital.


One hundred eighteen eyes of 89 patients with documented progressive mild to moderate keratoconus underwent corneal collagen cross-linking with riboflavin and UV-A, and followed up for a mean of 64 months (range 51-81 months). The primary measure was change in maximum K reading and secondary outcome was change in BCVA. Refraction, corneal thickness and endothelial cell count were also measured.


With a mean follow up of 64 months after cross-linking, maximum corneal curvature decreased by 2.4 D (P < .0001) and BCVA improved 1 or more lines in 62% of treated eyes (P < .05). No statistically significant difference in corneal thickness or endothelial cell density was found.


In this group of patients, long-term follow-up showed collagen crosslinking to be a safe and effective therapeutic option for progressive keratoconus.

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