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Combined photorefractive keratectomy and corneal collagen cross-linking

Poster Details

First Author: M.Afifi EGYPT

Co Author(s):                  

Abstract Details


1. To evaluate combined photorefractive keratectomy (PRK) and corneal collagen crosslinking (CXL), in thin and steep corneas, for treating myopic astigmatism. 2. To follow up corneal curvature, vision, and postoperative complications.


Research Institute of Ophthalmology (RIO), Cairo, EGYPT.


This study included twelve eyes of seven patients. Four were females and three males. Five were bilateral and two unilateral cases. Ages ranged from nineteen to thirty seven years (mean, 26.57). Least corneal thickness ranged from 477 to 529 microns ( mean, 495.58). Steepest K readings ranged from 43.5 to 48 diopters ( mean, 46.25). Optimized PRK was applied to all eyes followed simultaneously by CXL. Follow up was for 10 months.


Delayed epithelial healing occurred in two eyes (16.67%). Steroid glaucoma was found in three eyes (25%). Mild corneal haze remained for five months in one eye (8.3%). Postoperative best uncorrected visual acuity (BUCVA) was equal to preoperative best corrected visual acuity (BCVA) in nine eyes (75 %). It was less by on line on Snellen chart in three eyes (25%). There was significant visual improvement and patient satisfaction.


Combined PRK and CXL proved to be efficient in suspicious corneas and forme fruste keratoconus and keratoconus with acceptable pachymetry. BUCVA was satisfactory to all patients. No serious complications were encountered.

Financial Disclosure:


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