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Opacification of the Rayner hydrophilic acrylic intraocular lens implant after Descemet"s stripping endothelial keratoplasty (DSAEK)

Poster Details

First Author: R.De Cock UK

Co Author(s):    M. Fajgenbaum   D. Ledbetter           

Abstract Details


To highlight the incidence of intraocular lens (IOL) opacification after DSAEK and provide ultrastructural evidence of intra-optic calcification . A possible pathogenetic mechanism is presented.


Hospital based corneal surgical practice


Retrospective analysis of 108 DSAEK procedures performed between 2007 and 2012


4 cases of late opacification of the hydrophilic acrylic Rayner IOL were identified. 3 cases required a rebubble of air due to initial graft dehiscence. 1 case had undergone repeat DSAEK. Opacification involved only the optic of the IOL and was seen to be due to calcification within the IOL on ultrastructural and electron microscopic analysis


We postulate an interplay between postoperative inflammation leading to blood aqueous barrier breakdown and IOL surface changes due to air to account for the clinical and ultrastructural findings. We urge caution in the use of hydrophilic acrylic IOLs in DSAEK procedures

Financial Disclosure:


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