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Indications for corneal transplantation

Poster Details

First Author: M.Besharati IRAN

Co Author(s):    M. Shoja   N. Oveisi           

Abstract Details


This study was designed to investigate the indications for corneal transplantation in shahid sadooghi medical university as a referral hospital in yazd province.


Corneal transplantation is the most common allogenic tissue transplantation all around the world. Since the first successful corneal transplantation in 20 th century, its indications have significant changes. Advances in microsurgery, immunology, pharmacology and eye banking have caused great success that the indications for corneal transplantation are not the same around the world and also are changing through time.


this is a retrospective descriptive study that all case which undergo corneal transplantation were included. There were totally 351 corneal transplant surgeries done through the period. To investigate the corneal transplantation indications, all indications were categorized in 8 groups and then evaluated. The patient"s information were obtained from their medical records and then analyzed with SPSS software.


Of the 351 cases, 94.3% were transplanted with penetrating keratoplasty technique and the rest of them were transplanted with lamellar keratoplasty technique. In this study keratoconus was the most common indication for keratoplasty with the prevalence of 41.3%. it was more common in males than females. Corneal opacity and scar was the 2th common indication for keratoplasty. It accounted for 25.1 % of all indications. In most cases the cause of corneal opacity was not specified. Psudophakic corneal edema was the 3th common indication for keratoplasty. It accounted for 8.3% of all indications. The important point was the fact that most of the psudophakic patients were older than 60 years old. Regraft was the next common indication and accounted for 6.8% of indications.. The most common cause for regraft was corneal opacity and scar. Corneal dystrophy was the 5th common indication for corneal transplantation and accounted for 6.2% . macular corneal dystrophy and fuchs endothelial dystrophy were the most common dystrophies,respectively. Corneal perforation was a less common indication and accounted for 5.4% of all indications. The most common cause of corneal perforation was bacterial ulcer. Aphakic corneal edema was the least common indication for keratoplasty and accountes for just 2.3%.


As a conclusion keratoconous remain the leading indication for corneal transplantation in our center. By the way corneal opacity and scar is a common indication for keratoplasty and needs more concern. Although psudophakic corneal edema prevalence was lower than other reports from developed countries it seems it has increasing trend and may be of more concern with time goes on.

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