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Use of subconjunctival anti-VEGF injections in corneal neovascularisation

Poster Details

First Author: P.Gosciniewicz POLAND

Co Author(s):    D. Wygledowska-Promienska   G. Mazur-Piotrowska   A. Piotrowska-Gwozdz   L. Drzyzga     

Abstract Details



Purpose:

To investigate usefulness of subconjunctival anty-VEGF injections (Avastin) in inhibition of corneal neovascularisation

Setting:

Department of Ophthalmology, University Hospital No. 5, Medical University of Silesia, Katowice, Poland; Tommed, Katowice, Poland

Methods:

10 patients with severe corneal neovascularisation (5 after corneal transplant and 5 after infectious keratitis). Injection of Avastin at a dose of 1,25 mg was given subconjunctivally. Patiens were followed-up for 4 weeks, if inhibition result was unsatisfactory injection was repeated

Results:

Inhibition of corneal neovascularisation was observed after one week in all patients and continued for the whole period of observation. In three patients the therapy had to be repeated because of incomplete remission of neovascularisation

Conclusions:

Anty-VEGF therapy in subconjunctival injections exerts an inhibitory effect on corneal neovascularisation caused by different factors

Financial Disclosure:

NONE

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