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First Author: I.Lopes-Cardoso PORTUGAL
Co Author(s): F. Esteves M. Amorim J. Salgado-Borges
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To study the clinical outcome of canaloplasty in the treatment of open-angle glaucoma (OAG) simple or combined with phacoemusification
Ophthalmology Department CHEDV-Feira Santa Maria da Feira (Portugal)
Prospective study of the initial series of uncontrolled open-angle glaucoma patients or patients with cataract associated with OAG controlled or uncontrolled under maximal medical therapy that underwent canaloplasty alone or combined with cataract surgery respectively by a single surgeon. Complications, Goldmann intraocular pressure (IOP) and mean number of drugs (ND) were evaluated at 1 day, 1 week, 1-3-6 months, 1 year and 2 year.
Seventy six surgeries were performed (28 canaloplasties, 48 phaco-canaloplasties). The mean IOP (mmHg) dropped from 25.5 ±5.6, in canaloplasty, and from 22.2 ±10.3, in phacocanaloplasty, preoperatively, to medium-low levels at all follow-up periods (13.5 ±2.1 y 12.6 ±3.6, at 2 year in canaloplasty and phaco-canaloplasty respectively). ND dropped from 3.3 ±0.5 before surgery to under of 1 level in all follow-up periods (0.3 ±0.5 at 2 years). The complications were 5 microruptures of the trabeculodescemetic window, 15 transient hyphemas, 3 transient hypotonies, 1 hypotalamia, 2 peripheral Descemet detachments, 1 intracorneal hematoma, 3 peripheral anterior synechia, and 2 suture extrusions to the anterior chamber. Only corneal hematoma and 2 peripheral synechia needed subsequent surgical treatment. All the other complications were transient and didnṀt have a negative impact on success results.
Canaloplasty, alone or combined, provided sustained IOP reduction to medium-low levels, as well as in the ND, with a good safety profile and this makes it a good alternative to trabeculectomy.