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Inflammatory response in the anterior chamber after implantation of the Alcon AcrySof Cachet

Session Details

Session Title: Phakic IOL Implantation II

Session Date/Time: Wednesday 09/10/2013 | 08:00-10:30

Paper Time: 08:12

Venue: E104-105 (First Floor)

First Author: : S.Taneri GERMANY

Co Author(s): :    S. Oehler   C. Heinz           

Abstract Details


Some highly myopic eyes not deemed suitable for laser vision correction may be eligible for implantation of an anterior chamber intraocular lens for vision correction. However, this has been associated with anterior chamber inflammation in the past. We wanted to quantify the inflammatory response to a new foldable acrylic lens model over time.


Zentrum für Refraktive Chirurgie, Augenabteilung am St. Franziskus Hospital, Münster, Germany


Prospective study of 15 eyes of 15 adult patients with stable myopia >7 D, who were not eligible for full correction with an excimer laser. Exclusion criteria: Anterior chamber depth <3,2mm (measured including corneal thickness), insufficient endothelial cell density according to manufacturers age-related recommendations, other pre-existing ocular conditions, and prior eye surgery. Slitlamp examination and laser flare photometry were performed before and 1 day, 1 week, 1 month, 3 months, and 12 months after implantation of an Alcon Acrysof Cachet lens. Postop treatment includes antibiotic eye-drops for 5 days and non-steroidal anti-inflammatory eye-drops for 4 weeks. No steroidal eye-drops were administered.


Slitlamp evaluations of the anterior chamber revealed 0 to 10 cells within the measurement window (1mm x 1mm) at all preoperative exams and all follow-up visits. This corresponds to "0 to 1+" according to the SUN working group classification. Preop laser cell flare values were 8.29 (range 1.80 to 40.40) photons/ms, postop laser cell flare values were 18.96 (range 3.10 to 100.30)/ 23.56 (range 6.60 to 114.90)/ 15.33 (range 3.40 to 48.60)/ 14.87 (range 3.80 to 63.90)/ 10.00 (range 1.10 to 26.00) photons/ms 1 day/ 1 week/ 1 month/ 3 months/ 12 months after implantation of the Acrysof Cachet, respectively.


Results indicate a low maximum inflammatory response in the anterior chamber and a relative quick recovery of laser cell flare counts to safe values. An anti-inflammatory prophylaxis with non-steroidal eye-drops seems sufficient in routine cases; thus avoiding potential drawbacks of using corticoids.

Financial Interest:


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