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A prospective, randomized, eye-to-eye comparison of a 150 kHz femtosecond laser to a 60 kHz femtosecond laser for LASIK: 6-month results

Session Details

Session Title: LASIK

Session Date/Time: Wednesday 09/10/2013 | 08:00-10:30

Paper Time: 08:06

Venue: Auditorium (First Floor)

First Author: : E.Manche USA

Co Author(s): :    C. Yu              

Abstract Details


To prospectively compare LASIK outcomes between two femtosecond laser systems in the treatment of myopia. Outcome measures include high contrast snellen acuity, low contrast snellen acuity (25% and 5%), safety, efficacy, predictability and higher order aberration analysis.


University based academic refractive surgical service


One-hundred and twenty eyes of 60 consecutive patients were treated with wavefront-guided LASIK. One eye had a flap created with the AMO Intralase FS60 laser system and the fellow eye had a flap created with the AMO Intralase iFS 150 laser system. A 70 degree bevel-out side cut was used with the FS60 laser system and an inverted 130 degree bevel-in side cut was used with the iFS 150 laser system. Both lasers had a programmed flap thickness of 105 microns with a planned 9.0 mm superior hinged flap. Eyes were randomized according to ocular dominance. The mean pre-operative spherical equivalent refraction was -4.30 +/- 2.31 and -4.32 +/-2.31 in the iFS 150 group FS60 group respectively. There were no statistically significant differences in pre-operative higher order aberrations between the two groups.


At post op month six, 93% and 95% of eyes were within 0.50 diopters of the intended correction in the iFS 150 and FS60 groups respectively. At the 6-month post-op visit, the mean spherical equivalent refraction was -0.23 +/- 0.27 diopters in the iFS 150 group and -0.27 +/- 0.25 diopters in the FS60 group. At post-operative month six, there was an increase in total higher order aberrations from a preoperative value of 0.34 microns in both groups to 0.44 and 0.48 microns in the iFS 150 and FS60 groups respectfully. No eyes in either group lost more than one line of best spectacle corrected visual acuity.


Wavefront-guided LASIK using the iFS 150 femtosecond laser system for flap creation resulted in less induced total higher order aberrations compared to the FS60 femtosecond laser system at six months. There were no statistically significant differences in safety, predictability and efficacy between the two groups.

Financial Interest:


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