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Prospective randomized comparison of aspheric versus wavefront-guided photorefractive keratectomy: a contralateral eye study

Session Details

Session Title: Surface Ablation II

Session Date/Time: Tuesday 08/10/2013 | 16:30-18:00

Paper Time: 16:48

Venue: Main Lecture Hall (Ground Floor)

First Author: : S.Zarei-Ghanavati IRAN

Co Author(s): :    M. Abrishami   H. Gharaee           

Abstract Details


To evaluate the refractive, visual and aberrometric outcomes between wavefront-guided and aspheric photorefractive keratectomy (PRK) in myopic patients.


Khatam-al-Anbia Eye Hospital, Mashhad, Iran


In a randomized clinical trial, 96 eyes of 48 patients were enrolled in this prospective controlled study. In each patient, one eye was randomly assigned for treatment with the Zyoptix Wavefront-Guided PRK and the other eye was treated with Aspheric PRK, using Technolas 217z excimer laser (Bausch & Lomb). Preoperative, 3-month and 6-month postoperative refractive error, contrast sensitivity, visual acuity and high order aberrations (HOAs) were compared.


The mean spherical equivalent in the wavefront-guided PRK and the aspheric PRK was -0.076±0.029D and -0.077±0.075D, respectively (P=0.684). At the last postoperative visit, there was no differences between two groups for UCVA (P=0.987) and BCVA (P=0.416). Postoperatively the mean area under log of contrast sensitivity with and without glare was raised in comparison with preoperative visit (P=0.00). However, there was no difference between groups in contrast sensitivity with (P=0.903) and without (P=0.978) glare. Total HOAs increased after PRK in both groups; although aspheric PRK induced a smaller increase of postoperative HOAs compared to wavefront-guided PRK.


Both methods were safe and equally improved postoperative UCVA and contrast sensitivity. HOAs increased after treatment in both groups; however, aspheric ablation induced statistically fewer HOAs than wavefront-guided ablation.

Financial Interest:


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