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Photopic and mesopic visual function after small-aperture-inlay implantation

Session Details

Session Title: Intracorneal inlays for correction of presbyopia

Session Date/Time: Tuesday 08/10/2013 | 08:00-10:30

Paper Time: 08:18

Venue: Main Lecture Hall (Ground Floor)

First Author: : J.Pepose USA

Co Author(s): :                   Melles

Abstract Details


To evaluate and compare patientsÂ’ ability to perform day-to-day tasks under photopic and mesopic conditions preoperatively and 12 months postoperatively after implantation of a small aperture corneal inlay.


24 Clinics (US, Europe & Asia-Pacific)


A multicenter, prospective, non-randomized study in which a small aperture inlay was implanted monocularly in 507 emmetropic presbyopes. Preoperatively, spherical equivalent refraction was between +0.50D to -0.75D. Best-corrected distance visual acuities were 20/20 in both eyes and uncorrected near visual acuities ranged from 20/40 to 20/100 preoperatively. Patients were implanted with the inlay in the non-dominant eye in a femtosecond laser created lamellar pocket. At 24 months postoperatively, a patient questionnaire was administered to assess their ability to perform various near, intermediate and distance tasks with both eyes without glasses in both photopic and mesopic conditions. Task performance ability was scored on a scale of 1 (not easy at all) to 7 (very easy), and these interval changes were statistically compared.


Distance vision tasks included driving at night, driving during the day, participating in sports, judging distance, and watching movies or TV. For distance vision tasks, mean scores remained relatively constant, with preoperative values ranging from 5.7 to 6.8 postoperatively, compared to a range between 6.3 to 6.8 at 24 months post-op. Near and intermediate vision tasks such as reading newspapers, books, numbers on a mobile device, small print, and viewing a computer were evaluated under both mesopic and photopic conditions. Under mesopic conditions, the range of scores improved from between 1.14 to 1.72 preoperatively to between 2.37 and 4.0 postoperatively. Under photopic conditions, the average scores improved from between 1.34 and 2.18 preoperatively to between 3.61 and 4.86 postoperatively.


After inlay implantations, patients reported statistically significant improvements in their ability to perform distance, near, and intermediate tasks under various lighting conditions without glasses.

Financial Interest:

... receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented

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