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Determining the excimer laser ablation rate in the cross-linked (CXL) cornea

Session Details

Session Title: Keratoconus and ectasia

Session Date/Time: Tuesday 08/10/2013 | 16:30-18:00

Paper Time: 17:21

Venue: Elicium 2 (First Floor)

First Author: : O.Richoz SWITZERLAND

Co Author(s): :    S. Arba Mosquera   T. Magnago   F. Hafezi        

Abstract Details


A combination of collagen cross-linking (CXL) and surface ablation, simultaneously or serially, may be a promising means to correct part of the irregular astigmatism in corneal ectasia. Accordingly, surgeons will be confronted with patients that will present with previously cross-linked corneas requiring excimer laser ablation. Currently, the ablation rate per pulse in a cross-linked cornea is unknown.


Dept. of Ophthalmology, Geneva University Hospitals, Geneva, Switzerland


The laser excimer ablation rate of porcine corneas was analyzed using optical coherence pachymetry (OCP). The following conditions were analyzed: 1) normal cornea, with 5 consecutive ablations of 50 µm each. 2) normal cornea, previously soaked with riboflavin 0.1 %, cross-linked (18mW/cm2), and subjected to 5 consecutive ablations of 50 µm each. 3) normal cornea, previously soaked with riboflavin 0.1 %, cross-linked (3mW/cm2), with 5 consecutive ablations of 50 µm each.


The following ablation rates were obtained For no CXL: - 1X 50 µm 60 - 2X 50 µm 56 For CXL at 18 mW/cm2: - 1X 50 µm 53 - 2X 50 µm 44 For CXL at 3 mW/cm2: - 1X 50 µm 48 - 2X 50 µm 39


CXL seems to decrease the ablation rate of the cornea, this decrease seems to be more pronounced in a low fluence CXL (3 mW/cm2)

Financial Interest:

... gains financially from product or procedure presented, ... research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented, ... is employed by a for-monetary company with an interest in the subject of the presentation

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