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Mesenchymal stem ?ells in macular and optic nerve degeneration
Session Title: Ocular pathologies and training and innovation
Session Date/Time: Monday 07/10/2013 | 08:00-10:00
Paper Time: 09:34
Venue: Emerald (First Floor)
First Author: : P.Beliakouski BELARUS
Co Author(s): : M. Pazniak S. Pazniak M. Kovchel Sullivan
To assess the effectiveness of mesenchymal stem cells (MSCs) transplantation in macular degeneration and optic neuropathy treatment.
Ophthalmology Department of Tractor Plant Medical Centre, Minsk, Belarus
Four eyes of the patients were treated with the transplantation of 3 m autologic MSCs per eye. The injections were performed into subtenon capsules toward the posterior segment of the eyeball and followed by subsequent IV MSCs injections calculated as 1m per 1 kg of body weight. 2 hours before intravenous injection of MSC He-Ne and retinal laser stimulation of fovea centralis were performed. The clinical observation took from four to eight months.
No reliable changes in OCT data have been registered. There was registered 10-30 per cent (0.1-0.3) increase of visual acuity. In the field of vision there was registered a marked decrease in intensity of central scotoma.
MSCs autologic transplantation is a safe and effective method in treatment of macular degeneration and optic neuropathy.