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Session Title: Ocular pathologies and training and innovation
Session Date/Time: Monday 07/10/2013 | 08:00-10:00
Paper Time: 09:28
Venue: Emerald (First Floor)
First Author: : V.Dzinic SERBIA
Co Author(s): : M. Dzinic A. Oros
to show the results of combined procedures of cataract phacoemulsification and intravitreal anti-VEGF (Bevacizumab) application in patients with branch retinal vein occlusion and consecutive macular edema.
Private Eye center Dzinic, Vrsacka 34, 21000 Novi Sad, Serbia University Eye clinic Novi Sad, Serbia
5 patients (5 eyes) were planned for cataract surgery. Mean age was 54±9years, 4 female and 1 male, visual acuity (VA) ranges between 0.1 to 0.3 (Snellen chart), and nuclear hardness from N+1 N +3. During first examination branch retinal vein occlusion was observed and SD-OCT, and fluorescein angiography were conducted to confirm. Since the changes on fundus could not be examine in details due to cataract formation, cataract surgery was scheduled. All patients received 0,05ml (1,25mg) intravitreal anti-VEGF (Bevacizumab) 7 days before the cataract surgery. In all patients uncomplicated coaxial 2.75mm phacoemulsification technique was performed with temporal approach. Phacoemulsification was performed with B&L Millennium using pulse mode /35% to 45% US, 10 PPS , duty cycle 50%/. In all eyes single piece hydrophilic acrylic (B&L Adapt AO) lenses were implanted. Follow up visits were at the first and 7th day and one month after surgery and every 4-6 weeks after. All patients received topical tobramycin-dexamethasone eye drops 6 times daily for 4 weeks after surgery. Follow up period was 12 months.
In all patients successful cataract removal was achieved. No posterior capsule rupture was observed. Mean VA before the surgery was 0.18 ± 0.1 and average macular thickness 519±42µm. One month after the surgery mean VA was 0.61 ± 0.18 and average macular thickness was 229±37µm and remains stable during foolow-up period. In one eye additional anti-VEGF was adminstrated.
according to our study combining intravitreal application of anti-VEGF therapy and cataract surgery in patients with BRVO and macular edema have beneficial effect on visual acuity and macular stability during follow-up period. No adverse effects were observed. Larger studies and long-term follow-up is required to evaluate the safety and treatment durability.
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