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Big-bubble deep anterior lamellar keratoplasty using femtosecond laser with mushroom incisions versus a mechanical trephine in pediatric patients

Session Details

Session Title: Corneal Femtosecond

Session Date/Time: Monday 07/10/2013 | 14:30-16:30

Paper Time: 15:34

Venue: Elicium 1 (First Floor)

First Author: : L.Buzzonetti ITALY

Co Author(s): :    G. Petrocelli   P. Valente   S. Petroni        

Abstract Details


To evaluate the refractive outcome 16 months after big-bubble Deep Anterior Lamellar Keratoplasty (DALK) in pediatric patients performed using femtosecond laser with mushroom incisions or mechanical trephine.


Ophthalmology Department, Bambino Gesł IRCCS Children’s Hospital, Rome, Italy


Ten eyes of 10 patients affected by keratoconus were treated. Five eyes (Group 1) underwent big-bubble DALK by Hessburg Barron mechanical trephine (mean age 12?4.0?SD? years; range, 8 to 16 years) and 5 eyes (Group 2) by IntraLase 60 KHz (Abbott Medical Optics, Inc.) femtosecond laser with mushroom incisions. (mean age 14?3.6?SD? years; range, 8 to 10 years). Sutures were removed by 10 postoperative months in all patients. Spherical equivalent, refractive astigmatism and Best Corrected Visual Acuity (BCVA) were evaluated 16 months after surgery. The independent Student t test was used to compare each parameter between the 2 groups (P <0.05 was considered significant).


In Group 1 spherical equivalent and refractive astigmatism were -4.9?0.7?SD? and -5.8?3.3?SD? , while BCVA was 6.6?0.6?SD? . In Group 2 spherical equivalent and refractive astigmatism were -1.3?0.3?SD? and -2.6?0.7?SD?, while BCVA was 8.6?1.1?SD?. Only the spherical equivalent value showed significant changes between Group 1 and 2 (p<0.05).


These findings suggest that in pediatric patients the big-bubble DALK assisted by femtosecond laser compared to the mechanical trephine seems to improve the refractive outcome.

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