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Single-step transepithelial PRK vs alcohol-assisted PRK in myopia and compound myopic astigmatism correction

Session Details

Session Title: Surface Ablation I

Session Date/Time: Sunday 06/10/2013 | 08:00-09:30

Paper Time: 09:06

Venue: Main Lecture Hall (Ground Floor)

First Author: : B.Kaluzny POLAND

Co Author(s): :    I. Cieslinska              

Abstract Details


TransPRK is a new variant of transepithelial PRK in which both epithelium and stroma are removed in a single step, with respect to a population model of epithelial thickness. The aim of this study is to compare 3-month results of myopia and compound myopic astigmatism correction with TransPRK and alcohol-assisted PRK.


Oftalmika Eye Hospital, Department of Ophthalmology of Collegium Medicum NCU, Bydgoszcz, Poland


Of a total 131 patients aged ?21 years, 68 (125 eyes) underwent TransPRK and 63 (115 eyes) underwent alcohol-assisted PRK for low to moderate myopia or compound myopic astigmatism. Mean preoperative manifest refraction spherical equivalent (MRSE) was -3.93 D ± 1.89 D (-1.13 to -8.25 D) and -3.81 D ± 1.81 D (-0.90 to -7.75) respectively. All procedures were performed with the Amaris 750S (Schwind, Germany). In PRK group in eyes with preop spherical equivalent above -4.0 and in all cases of TransPRK 0.02 % MMC was applied for 2 min. Refractive results, predictability, safety, and efficacy were evaluated 3 months after the surgery.


Mean postoperative MRSE was -0.12 D ± 0.25 D, mean cylinder -0.09 ± 0.22 D in TransPRK group, in PRK group -0.11 ± 0.21 and 0.08 ± 0.18 D, respectively (p>0.05). The correlation between attempted versus achieved MRSE was very high in both groups (y=0.99x R2=0.99; p>0.05). All treated eyes were within ±0.50 D of attempted spherical correction, 67% were within ±0.25 D in TransPRK group and 77% in PRK group (p>0.05). In TransPRK group statistically more often attempted spherical correction was within the range of +0.126 to +0.50, in 14% of eyes, in comparison to 3% in PRK group. Uncorrected distance visual acuity after the surgery was 20/20 or better in 97% of eyes in TransPRK group and 94% in PRK group (p=0.05). In TransPRK group 14% of eyes lost one line of CDVA and 26 % gained a line or two, in PRK group it was: 16% and 29% (p>0.05). In postoperative course, a minimal haze was noted in 13 % of eyes after TransPRK and in 10 % of eyes after PRK (p>0.05). Statistically significant differences between groups in other intraoperative or postoperative complications as well in postoperative pain were not noted.


TransPRK and alcohol-assisted PRK with the Amaris 750S provide very similar results 3 months after the surgery. Those procedures are predictable, effective and safe for myopia and compound myopic astigmatism correction.

Financial Interest:

... travel has been funded, fully or partially, by a company producing, developing or supplying the product or procedure presented

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