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Corneal sensation after small incision lenticule extraction (SMILE) compared to previous LASIK studies

Session Details

Session Title: Refractive Femtosecond

Session Date/Time: Sunday 06/10/2013 | 17:00-18:30

Paper Time: 17:42

Venue: Elicium 2 (First Floor)

First Author: : M.Gobbe UK

Co Author(s): :    D. Reinstein   E. Bartoli   T. Archer        

Abstract Details


To longitudinally evaluate the recovery of central corneal sensation after small incision lenticule extraction (SMILE) and compare this to data from published studies after LASIK.


London Vision Clinic, London, UK


A retrospective non-comparative case series included 156 myopic eyes of 80 consecutive patients treated with SMILE using the VisuMax femtosecond laser (Carl Zeiss Meditec). Central corneal sensation was measured using a Cochet-Bonnet aesthesiometer before and 1 day, 1 week, 1, 3, and 6 months after the procedure. Baseline was defined as the 5mm less than the preoperative value. A literature search was performed to find published studies reporting central corneal sensation using a Cochet-Bonnet aesthesiometer before and after LASIK. The data from these studies was averaged and used as a comparison for the SMILE population.


Mean maximum myopic meridian treated was -7.16±2.58 D (range: -2.25 to -12.78 D). Median age was 33 years (range: 19 to 66 years). After SMILE, central corneal sensation dropped from 54 mm preoperatively to 32 mm on day one, rising to 40 mm at 1 week, 44 mm at 1 month, 49 mm at 3 months and 50 mm at 6 months. Corneal sensation had returned to baseline by 1 month in 62%, by 3 months in 77% and by 6 months in 80% of eyes. Twenty studies were identified that reported central corneal sensation after LASIK and the data were averaged at each time point; the central corneal sensation dropped from 56 mm preoperatively to 9 mm at day one, rising to 15 mm at 1 week, 22 mm at 1 month, 33 mm at 3 months, 44 mm at 6 months and 50 mm at 12 months. Across the LASIK studies, the mean spherical equivalent refraction treated was -4.3 D and mean age was 34.2 years.


There was less reduction in central corneal sensation after SMILE than after LASIK at all time points and recovery to normal levels was reached in the majority of patients by 3 months after SMILE compared with 6-12 months after LASIK.

Financial Interest:

... receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented

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