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Comparison of straylight measured in vivo and in vitro for different intraocular lens designs

Session Details

Session Title: IOL Technology

Session Date/Time: Sunday 06/10/2013 | 16:30-18:30

Paper Time: 17:17

Venue: Auditorium (First Floor)

First Author: : L.Franssen THE NETHERLANDS

Co Author(s): :    M. Langeslag   M. van der Mooren   H. Dick   U. Mester   P. Piers  

Abstract Details


To compare the influence of intraocular lens (IOL) design on straylight measured in vivo (pseudophakes) and in vitro (laboratory setup) at different scatter angles.


AMO Groningen BV, Groningen, The Netherlands; Universit├Ątklinikum Knappschaftskrankenhaus Bochum, Bochum, Germany; Augenzentrum im Medizeum, Saarbr├╝cken, Germany


Intraocular straylight was measured in vivo 3 months postoperatively with the C-Quant (Oculus) in 71 pseudophakic eyes implanted with either a monofocal (spherical acrylic (N=16), aspheric acrylic (N=17), aspheric silicone (N=13)) or multifocal (acrylic diffractive (N=12), silicone diffractive (N=13)) IOL. In 25 eyes with monofocal IOLs, straylight was also measured with an adapted C-Quant, which measures at an average angle of 3.5 degrees instead of the standard 7 degrees. Straylight was also measured in vitro at scatter angles between 1.5 and 22 degrees in IOLs of the same types in a laboratory goniometer setup. During these measurements, the IOLs were placed in a saline-filled cuvette to mimic the in vivo situation.


The average 3-month postoperative straylight values for the 3 monofocal groups were not statistically significantly different (log(s) between 1.26 and 1.37 for 7 degrees, log(s) between 1.41 and 1.45 for 3.5 degrees). For 7 degrees, the average value for the multifocal group (log(s)=1.32) was almost the same as for the monofocal group (log(s)=1.31). Although the in vitro straylight results were substantially lower (log(s) typically around 0.1), the same trends were observed as in vivo: straylight not dependent on design and material for the monofocal IOLs, lower straylight levels with increasing scatter angle, and similar results for mono- and multifocal IOLs at larger scatter angles.


Although in vitro straylight levels of IOLs are lower than in vivo levels (which also contain straylight contributions of other ocular media), they show similar trends in terms of angular dependence and influence of optical design and material at larger scatter angles.

Financial Interest:

... is employed by a for-monetary company with an interest in the subject of the presentation

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