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Session Title: IOL Technology
Session Date/Time: Sunday 06/10/2013 | 16:30-18:30
Paper Time: 16:36
Venue: Auditorium (First Floor)
First Author: : H.Weeber THE NETHERLANDS
Co Author(s): : R. Pohl U. Mester P. Piers
Previous theoretical studies using computer simulations and experiments using a visual simulator have shown that the simultaneous correction of longitudinal spherical aberration (LSA) and longitudinal chromatic aberration (LCA) can improve visual performance. The aim of the current study was to demonstrate the visual performance of intraocular lenses correcting both spherical and chromatic aberration in a clinical setting.
1) AMO Groningen, Netherlands; 2) AMO Germany GmbH, Ettlingen, Germany, 3) Eye Center in Medizeum, Saarbrücken, Germany
In a prospective, subject-masked, paired-eye, randomized multicenter clinical study, 20 subjects with uncomplicated bilateral cataracts had standard small-incision cataract surgery. An IOL correcting both LCA and LSA (IOL1) was implanted in one eye, and an IOL correcting LSA only (IOL2) was implanted in the other eye. Both IOL designs shared the same IOL platform (IOL material, optic, and haptics) and differed only in their aberration correction. Both lenses were CE marked. Visual performance of each eye was tested at 1 month and 3 months postoperatively.
At 1 month, best corrected visual acuity was 0.05 logMAR for the IOL1 eyes and 0.01 logMAR for the IOL2 eyes, showing no significant difference (p=0.15). At 3 months, the differences were comparable: 0.06 logMAR for the IOL1 eyes and 0.02 logMAR for the IOL2 eyes (p=0.10). The subjects with good high-contrast VA (BCVA ≤ 0.0 logMAR; n=13) showed a higher gain in visual acuity (p<0.05). This is in accordance with experiments showing that correction of LCA has a more positive effect on visual quality when monochromatic aberrations are also corrected. Contrast acuity was better for eyes having IOL1 for all contrast levels. However, statistical significance was not reached (p value ≥ 0.18).
The clinical data suggest that combined correction of longitudinal chromatic aberration and spherical aberration may have a positive effect on visual performance. The results are in agreement with previous studies using computer simulations, as well as subjective testing using a vision simulator.
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