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10 - 12 February 2017, MECC Maastricht,The Netherlands.

This Meeting has been awarded 15 CME credits.


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Topography-guided photorefractive keratectomy with accelerated corneal collagen cross-linking (KXL) in mild to moderate keratoconus

Poster Details

First Author: K. Chopra INDIA

Co Author(s): V. Bhandari   S. Ganesh                 

Abstract Details


To evaluate the results of simultaneous topography guided photorefractive keratectomy (PRK) with accelerated corneal collagen crosslinking (KXL) in the management of mild to moderate keratoconus


Cornea And Refractive Department, Nethradhama Superspeciality Eye Hospital, Bangalore, India.


In this prospective, interventional study, 16 patients (24 eyes) with mild to moderate keratoconus and pachymetry more than 400 microns were treated with Topography guided PRK with the Mel-90 Excimer LASER (Carl Zeiss Meditec AG, Jena, Germany; wavelength 193nm) with accelerated corneal collagen crosslinking KXL(Avedro KXL, Waltham, MA, USA) with the use of riboflavin and ultraviolet A irradiation. Patients were followed up for six months. Topographic parameters, visual acuity and endothelial cell count were monitored. Pre- and post-operative parameters were compared.


Preoperative mean Specular Endothelial Count was 2620 +/- 156 cells/mm2 which decreased to 2529 +/- 107 cells/mm2 at six months post operative follow up. Preoperative mean (logMAR) uncorrected visual acuity was 0.49 +/- 0.28 and best spectacle-corrected visual acuity was 0.18 +/- 0.1, which improved postoperatively to 0.28 +/-0.29 (p< 0.05) and 0.08 +/- 0.08 (p<0.05), respectively. The mean steepest keratometry was reduced from 45.4 +/- 3.7 D preoperatively to 43.2+/- 2.9D at six months follow-up.


Simultaneous topography guided photorefractive keratectomy (PRK) with accelerated corneal collagen crosslinking (KXL) is a promising treatment which can provide functional vision in patients with mild to moderate keratoconus.

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